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锟斤拷锟斤拷然锟斤拷锟斤拷锟揭囷拷锟斤拷锟斤拷锟絫藥锟斤拷锟斤拷锟皆达拷锟斤拷原始锟斤拷锟铰短板，锟斤拷锟斤拷锟节勶拷锟斤拷锟叫撅拷缺锟斤拷锟斤拷锟紻锟斤拷锟斤拷锟絰锟斤拷锟铰機锟狡★拷锟铰帮拷锟絚锟斤拷锟絉锟斤拷锟叫撅拷锟結源锟斤拷锟姐；锟叫發锟桔硷拷锟节燂拷锟絋锟斤拷锟絚锟紽锟斤拷锟斤拷锟紷锟斤拷锟秸憋拷锟斤拷锟酵拷|锟斤拷锟饺凤拷锟芥。未锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷蝺锟斤拷锟斤拷锟斤拷膭睢拷锟斤拷锟斤拷锟街э拷謩锟斤拷锟剿庯拷l展锟斤拷锟节斤拷锟斤拷锟饺拷锟斤拷蓵锟斤拷希锟斤拷锟轿伙拷舜锟斤拷锟斤拷锟斤拷锟紷一話锟絵锟斤拷锟斤拷锟斤拷锟斤拷P锟斤拷锟絟锟斤拷

锟斤拷锟斤拷锟斤拷锟斤拷锟叫發锟斤拷锟窖現锟斤拷锟斤拷锟斤拷凸锟紷

锟斤拷锟斤拷锟斤拷2021锟疥“聲锟斤拷锟斤拷責锟轿★拷锟絫藥锟絣锟斤拷锟斤拷锟剿达拷锟斤拷锟斤拷锟斤拷锟斤拷f委锟絋锟斤拷談锟斤拷锟较ｏ拷全锟斤拷锟剿达拷锟斤拷锟斤拷锟斤拷锟斤拷K锟斤拷锟斤拷锟絫藥锟斤拷锟紽锟斤拷锟睫癸拷司锟斤拷锟斤拷锟絃锟絆锟絟锟絇锟斤拷示锟斤拷锟揭囷拷锟侥勶拷锟斤拷藥锟叫堬拷锟斤拷锟斤拷锟絕锟斤拷锟截復的嗭拷锟絵锟斤拷锟斤拷锟斤拷PD-1锟斤拷锟斤拷锟斤拷锟斤拷偷陌锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷PD-1锟芥及锟斤拷锟絤锟斤拷锟紺锟斤拷V锟斤拷锟叫堬拷也锟筋急锟借，锟斤拷I锟絜锟絆锟皆很高ｏ拷锟斤拷锟斤拷锟結锟斤拷锟斤拷锟狡诧拷锟斤拷锟斤拷锟斤拷PD-1锟斤拷锟斤拷沫锟斤拷锟矫很高★拷锟斤拷

锟斤拷锟斤拷PD-1锟叫堬拷賽锟斤拷锟斤拷D锟斤拷锟窖斤拷锟缴烇拷锟叫業锟斤拷锟絉锟斤拷3锟斤拷5锟秸ｏ拷锟狡勶拷锟斤拷锟斤拷锟叫癸拷司锟劫奧泰锟斤拷锟斤拷锟終止锟缴匡拷锟斤拷锟斤拷锟斤拷藥锟斤拷锟絉锟斤拷試驗，锟斤拷锟斤拷一锟斤拷锟斤拷锟截組锟斤拷源锟斤拷锟斤拷PD-1锟轿匡拷隆锟斤拷锟絯注锟斤拷液锟斤拷锟斤拷锟节終止PD-1藥锟斤拷锟叫發锟斤拷锟劫奧泰锟斤拷B锟斤拷锟侥革拷锟斤拷PD-1锟轿匡拷锟斤拷锟絉锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟紸計未锟斤拷2锟斤拷-3锟疥，全锟斤拷锟斤拷锟斤拷PD-1锟絘品锟斤拷锟斤拷锟杰筹拷锟絕20锟斤拷锟斤拷锟叫堬拷锟斤拷锟斤拷锟斤拷趨锟斤拷锟揭★拷锟叫囷拷锟斤拷PD-1锟斤拷锟斤拷锟筋激锟揭的地區锟斤拷全锟斤拷154锟斤拷PD-1锟斤拷锟斤拷锟斤拷85锟斤拷锟斤拷锟叫囷拷锟斤拷I锟叫發锟斤拷锟斤拷锟斤拷_锟絣锟斤拷占锟斤拷锟絖锟斤拷55%锟斤拷PD-1全锟斤拷蛧锟斤拷鹊锟絇D-1锟轿匡拷锟斤拷锟叫發賽锟斤拷锟窖斤拷變锟矫擄拷D锟斤拷锟斤拷锟斤拷锟斤拷邪l锟斤拷品也锟接勶拷锟剿岋拷CRO锟斤拷司锟斤拷锟絫藥锟斤拷锟斤拷邪l锟斤拷锟秸機锟斤拷锟斤拷锟侥革拷锟斤拷锟斤拷使锟斤拷锟絖锟絣锟缴憋拷锟組一锟斤拷锟接勶拷锟斤拷

锟斤拷锟斤拷值锟斤拷一锟斤拷锟斤拷牵锟斤拷锟斤拷鲁锟斤拷锟絇D-1之锟解，锟斤拷锟絋锟斤拷锟絚BTK锟斤拷PARP锟斤拷也锟角囷拷锟饺勶拷锟斤拷藥锟斤拷锟叫發锟斤拷锟斤拷锟絀锟斤拷

锟斤拷锟斤拷锟斤拷锟斤拷锟铰ｏ拷锟斤拷锟斤拷锟窖斤拷锟叫诧拷锟斤拷锟斤拷I锟竭傦拷锟絕锟斤拷锟斤拷模锟铰勶拷锟斤拷锟斤拷锟斤拷锟斤拷锟杰夛拷锟斤拷俑锟桔欙拷锟斤拷锟斤拷殉锟剿庯拷锟斤拷掳锟斤拷c锟斤拷锟組锟斤拷me-too锟斤拷me-better藥锟斤拷锟斤拷_锟絣锟斤拷锟紷也锟斤拷锟斤拷锟斤拷锟絀锟斤拷锟斤拷追锟斤拷獭锟狡斤拷锟斤拷锟侥產锟斤拷锟斤拷锟斤拷锟斤拷追锟斤拷锟斤拷c锟斤拷同锟絴锟斤拷锟斤拷锟斤拷锟斤拷锟截ｏ拷锟斤拷锟铰达拷锟斤拷锟斤拷锟結源锟斤拷锟組锟斤拷锟斤拷锟斤拷锟斤拷锟絫藥锟叫業锟斤拷锟絃锟节發展锟斤拷锟斤拷全锟斤拷锟剿达拷锟斤拷锟斤拷锟斤拷袊锟剿庯拷贂锟斤拷锟斤拷锟斤拷L锟斤拷貝锟絖藥锟絀锟斤拷锟斤拷锟絃锟斤拷锟斤拷席锟斤拷锟叫官讹拷锟斤拷锟斤拷锟节斤拷锟杰★拷锟紺券锟秸堬拷記锟竭诧拷锟絃锟絩锟斤拷示锟斤拷

锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟接快審锟絬锟斤拷锟斤拷 锟斤拷锟斤拷锟斤拷锟斤拷藥锟絣展

锟斤拷锟斤拷2020锟斤拷1锟斤拷22锟秸ｏ拷锟斤拷锟斤拷锟叫堬拷锟絆锟斤拷锟斤拷锟斤拷锟斤拷锟街癸拷锟斤拷锟铰版《藥品注锟皆癸拷锟斤拷锟絢锟斤拷锟斤拷锟斤拷锟节凤拷锟缴的岋拷锟斤拷锟斤拷锟組一锟斤拷锟侥勶拷锟絫藥锟斤拷锟铰★拷然锟斤拷锟斤拷锟斤拷锟斤拷胃锟斤拷锟剿斤拷锟斤拷锟斤拷锟巾攲锟斤拷O計锟斤拷锟絪小锟絚锟絣锟絖锟斤拷锟揭诧拷啵拷M一锟斤拷锟斤拷锟斤拷原始锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷讓锟斤拷锟斤拷锟組一锟斤拷锟斤拷氐确锟斤拷锟斤拷覈锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷蛢锟斤拷锟斤拷锟斤拷g锟斤拷锟斤拷锟斤拷锟叫業锟斤拷锟铰發展锟斤拷锟节的嗭拷锟絵锟斤拷锟斤拷锟巾們也锟給锟斤拷锟斤拷锟斤拷锟絇锟斤拷锟絟锟斤拷

锟斤拷锟斤拷锟絆锟絟锟絇指锟斤拷锟斤拷锟斤拷锟斤拷通锟絕頂岋拷锟絆計锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷藥锟叫發投锟诫。锟斤拷锟解，锟斤拷锟接快審锟絬锟斤拷锟斤拷锟斤拷锟絪小锟絚锟斤拷锟斤拷牟锟洁，讓锟斤拷锟斤拷藥锟斤拷锟絚锟斤拷锟剿庯拷锟秸撅拷锟酵伙拷锟斤拷芫锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟剿庯拷r值锟絯系锟斤拷锟斤拷锟斤拷锟斤拷I锟斤拷锟斤拷锟斤拷锟侥勶拷锟铰ｏ拷锟斤拷锟結锟斤拷锟矫碉拷锟絇锟絀锟侥地凤拷锟斤拷锟斤拷锟解，還要锟斤拷Q锟斤拷锟斤拷藥锟組锟斤拷锟絫锟斤拷目錄猴拷锟斤拷锟斤拷一锟斤拷锟斤問锟絵锟斤拷

锟斤拷锟斤拷锟斤拷2020锟斤拷锟酵伙拷锟斤拷锟斤拷锟斤拷锟铰冠凤拷锟斤拷锟斤拷锟介，锟組一锟斤拷凸锟紷锟斤拷藥锟斤拷锟斤拷锟斤拷锟斤拷锟铰碉拷锟斤拷要锟皆和緊锟斤拷锟皆★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟紺券锟秸堬拷記锟竭憋拷示锟斤拷锟揭傦拷锟斤拷要锟接忥拷锟斤拷锟斤拷锟斤拷锟铰ｏ拷锟紷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟絊锟給锟斤拷锟斤拷锟絫锟斤拷锟絣锟斤拷锟斤拷锟皆帮拷全锟斤拷锟斤拷锟斤拷十锟斤拷锟斤拷要锟斤拷锟斤拷锟絰锟斤拷锟斤拷锟斤拷锟組一锟斤拷锟斤拷锟斤拷锟斤拷锟絘锟斤拷锟斤拷藥锟斤拷锟絬锟斤拷锟斤拷锟斤拷锟津，加匡拷锟斤拷锟斤拷锟斤拷锟斤拷藥锟斤拷锟叫岋拷锟斤拷锟劫度ｏ拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷c锟斤拷锟絟锟斤拷锟斤拷锟絟锟組一锟斤拷锟接忥拷锟斤拷息锟斤拷锟絖锟斤拷锟饺ｏ拷锟組一锟斤拷锟斤拷锟斤拷目锟斤拷锟絬锟斤拷通效锟绞ｏ拷锟斤拷锟絟锟絗锟斤拷芽锟斤拷锟斤拷锟斤拷R锟斤拷锟叫撅拷锟斤拷锟絞锟斤拷锟絬要锟襟；斤拷锟絟財锟斤拷锟较給锟斤拷CDE(锟斤拷锟斤拷藥锟絆锟斤拷藥品锟斤拷锟絬锟斤拷锟斤拷)锟斤拷锟洁經锟組支锟街ｏ拷锟斤拷锟斤拷藥品锟斤拷锟絬锟剿員锟侥革拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟接岋拷锟絬锟剿員锟斤拷锟斤拷锟斤拷

锟斤拷锟斤拷锟絉锟斤拷锟斤拷藥锟斤拷锟斤拷锟斤拷锟斤拷锟节斤拷锟杰★拷锟紺券锟秸堬拷記锟竭诧拷锟絃锟絩锟斤拷示锟斤拷锟斤拷锟絟锟接忥拷锟斤拷锟紸锟叫撅拷锟斤拷锟斤拷锟斤拷锟皆★拷锟斤拷藥锟斤拷锟叫★拷锟斤拷锟斤拷牡锟斤拷t藥锟斤拷锟铰★拷锟斤拷锟斤拷锟斤拷锟较ｏ拷一锟角斤拷锟絟锟斤拷锟絤锟組锟叫岋拷锟絬锟斤拷锟斤拷锟狡度改革，锟斤拷锟斤拷锟斤拷锟絬锟斤拷锟斤拷锟斤拷锟絴锟斤拷锟斤拷效锟绞ｏ拷锟节憋拷锟较帮拷全锟皆碉拷前锟斤拷锟铰岋拷锟斤拷锟斤拷責锟斤拷锟絰锟斤拷锟斤拷I锟斤拷锟紺锟斤拷锟斤拷锟叫堬拷锟斤拷锟斤拷锟斤拷锟組一锟斤拷锟狡勶拷锟叫囷拷藥品注锟皆標準科學锟斤拷锟絣展锟斤拷锟接匡拷藥品注锟皆硷拷锟絞要锟斤拷锟絚锟斤拷锟紿要锟斤拷膮f锟絳锟統一锟斤拷锟斤拷锟斤拷锟組一锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷锟絉锟斤拷锟叫撅拷锟絯系锟斤拷锟斤拷锟斤拷锟絉锟斤拷锟叫撅拷锟紺锟斤拷锟絎锟絡锟斤拷锟戒實锟絉锟斤拷锟叫撅拷锟侥勶拷C锟狡ｏ拷支锟斤拷锟絫院锟斤拷锟紺锟斤拷锟絚锟剿員锟絖展锟絉锟斤拷試驗，锟斤拷锟絉锟斤拷試锟絣锟斤拷锟斤拷锟斤拷锟斤拷锟絬锟絩锟絳锟斤拷锟絫锟斤拷锟紺锟斤拷锟饺硷拷锟絬锟斤拷锟斤拷锟斤拷锟絖展锟絉锟斤拷試锟斤拷锟絫锟斤拷锟紺锟斤拷锟斤拷锟斤拷锟轿拷锟絬锟絩锟斤拷锟斤拷锟絯系锟斤拷锟侥勶拷锟絫锟斤拷锟紺锟斤拷锟絆锟斤拷锟斤拷職锟絉锟斤拷試驗部锟絋锟斤拷锟斤拷锟斤拷锟絉锟斤拷試锟斤拷锟斤拷P锟斤拷锟斤拷锟绞╋拷锟斤拷锟斤拷锟斤拷锟斤拷c锟絉锟斤拷試锟侥積锟絆锟皆★拷锟斤拷锟斤拷锟斤拷锟斤拷锟斤拷

锟斤拷锟斤拷 锟紻锟皆ｏ拷锟紺券锟秸堬拷